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This antibody, when interacting with PD-1, reinstates cytokine release from activated T cells, effectively blocking both the HGF/c-MET and PD-1/PD-L1 signaling pathways [144]

3.3 Treatment strategies Calcium channel blockers, such as amlodipine, have shown promise in preventing cocaine-induced vascular toxicity by lowering blood pressure and reducing headache frequency (Malcolm et al., 2002

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