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10.1038/nature04056 [DOI] [PubMed] [Google Scholar] Csotonyi JT, Stackebrandt E, & Yurkov V (2006)

a process associated with aggressive proliferation and poor patient prognosis (69,70)

Moreover, it promotes mitochondrial damage via reactive oxygen species (ROS) accumulation [30] and synergizes with doxorubicin (DOX) to exert potent antitumor effects [31]