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45 KondoT.AsaiM.TsukitaK.KutokuY.OhsawaY.SunadaY.et al (2013)

[2.] It is studied for its involvement in actin binding and cytoskeletal organization as observed in mammalian models

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The reason stacking raises safety questions is simple: when you combine signals, you can also combine side effects, sensitivities, and unintended downstream effects