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Within this complex, RAPTOR interacts with the N-terminal region of mTOR, playing a critical role in complex assembly, subcellular localization, stability, and substrates recruitment

Overall, our results show that a subset of chloroacetamides (including SCLA1, SCLA2 and SCLA3) engages GPX4 to induce ferroptosis in senescent cells

Single-agent optimization typically outperforms combination protocols in real-world practice

Although cyst(e)ine levels did not fully recover, presumably because of impaired cystine reabsorption due to sustained tubular injury by sulfasalazine, , cystine levels tended to increase in the sulfasalazine group

Hypoxia and reproductive health: oxygen and development of the human placenta