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Recent studies highlight circadian-targeted approaches for BBB repair after stroke, including mesenchymal stem cellderived exosomes (160) and herbal compounds (161, 162), which act in part by modulating clock gene expression

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doi: 10.3390/life12111856

Reactions contained 0.8 mM substrate (arogenate or prephenate) and 0.8 mM cofactor (NADP + or NAD + ) together with reaction buffer [25 mM HEPES pH 7.6, 50 mM KCl, 10% (v/v) ethylene glycol]

At 3 hours after pMCAO, it influenced the expression of genes regulating the activity of immune cells such as macrophages, neutrophils, and lymphocytes