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There have been no large-scale studies on humans, and its role as a clinical therapy is considered scientifically controversial

It can also help prevent cell apoptosis which helps maintain cell viability and contribute to overall mitochondrial function

Conover CA, Lee PD, Kanaley JA, Clarkson JT, Jensen MD

A 500mcg daily protocol under split dosing would look like: 300mcg upon waking (fasted), then 200mcg approximately 30 minutes before dinner or before bed on an empty stomach

Because it uses the active methylated form of B12 (methylcobalamin), it provides faster, more effective results than standard cyanocobalamin supplements