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The best-fit patients include: Patients with a documented or strongly suspected deficiency low B12, malabsorption from GI conditions, or diets that predispose to nutrient gaps where IV correction has a clear rationale

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A higher surface area definitely enhances contact with bacterial membranes and pollutant molecules, while specific facets and defects promote reactive oxygen species (ROS) generation, eventually improving photocatalytic activity 46

Cell Death Differ 11(Suppl 1):S73S85 Gallogly MM, Starke DW, Mieyal JJ (2009) Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulation

Persaud AT, Khela J, Fernandes C, Chaphekar D, Burnie J, Tang VA et al (2024) Virion-incorporated CD14 enables HIV-1 to bind LPS and initiate TLR4 signaling in immune cells