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10.1039/c6fo00773b 113 WangY.WangZ.GaoM.ZhongH.ChenC.YaoY.et al (2019)

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Rather, this lethal process is centered on the iron-dependent, oxidative destruction of membrane lipids

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It initiates the expression of several downstream antioxidants, anti-inflammatory proteins and detoxification enzymes through the Kelch-like ECH-associating protein 1 (Keap1) -nuclear factor E2-related factor 2(Nrf2) -antioxidant response element (ARE) signaling pathway