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This proposes that, ISC is the key of how DNA glycosylases distinguish the intact and damaged bases

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Aside from these common symptoms, candida overgrowth may also play a role in: Infertility Fatigue Brain fog Weight gain Weakness and muscle pain Gas, bloating, diarrhea, and constipation Muscle and joint pain Depression Food sensitivities To see how candida, Hashimotos, and hormonal shifts might interconnect, imagine three legs of a stool: The immune system (autoimmunity, inflammation) The gut environment (microbiome, intestinal permeability) The endocrine/hormonal system (thyroid hormones, estrogen, progesterone, cortisol) When one leg is off balance, the stool cant stand easily