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The Disruption of L-Carnitine Metabolism by Aluminum Toxicity and Oxidative Stress Promotes Dyslipidemia in Human Astrocytic and Hepatic Cells

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NNMT knockdown in a more aggressive squamous cell line contributed to the downregulation of epithelialmesenchymal transition (EMT)-related genes, including MMP9 , osteopontin ( OPN ), and versican core protein ( VCAN ), which are involved in focal adhesion and extracellular matrix (ECM)receptor interaction ( Cancer-associated fibroblasts (CAFs) are a fibroblast subpopulation that secrete pro-oncogenic cytokines and ECM-modifying factors promoting and supporting malignant cell growth and invasion (75)

10.1016/j.mad.2020.111215 16 ChenL.-Y.WangY.TerkeltaubR.Liu-BryanR

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