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Targeting the TRIM65-K206 lactylation site or reducing lactate production via sodium-glucose cotransporter 2 inhibitors restores the dual inhibition of ferroptosis and glycolysis by TRIM65 (58)

Then, stained cells were washed 5 with PBS and mounted on slides with mounting media containing DAPI (ProLong Glass Antifade Mountant, Invitrogen, cat#: P36980)

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Hung et al., 2020)

Several clinical studies have demonstrated the therapeutic effect of SOD on radiation-induced injury, such as GC4419 (Avasopasem, a synthetic SOD mimetic), which can alleviate mucositis in head and neck radiotherapy (131)