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Although the chemical structure of EGT is relatively simple (Fig

Effect of TrxR inhibition on Vs activity To evaluate the effect of the Trx/TrxR redox system on the activity of Vs, U1Grx1roGFP2 cells were treated with increasing concentrations of TrxR inhibitor, auranofin (125, 250, and 500 nM) for 16 h

In the liver, MRI-derived proton density fat fraction has been widely used to quantify liver fat content and has been the focus of early clinical trials of antifibrotic drugs in non-alcoholic steatohepatitis [268]