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The copper component of the peptide serves as an essential cofactor for lysyl oxidase and lysyl hydroxylase , enzymes critical for proper collagen cross-linking and stability

Both accelerate cell turnover, and using them together can overwhelm the skin

Gradual changes escape notice

All animals were bred in the pathogen-free facility with a 12 h light/dark cycle at temperature (2025 C), relative humidity (4060%), and had ad libitum access to food and water