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In Alzheimers disease, vitamin E has been extensively investigated for its potential role in reducing amyloid and tau pathology, two key hallmarks of the disease

Smaller molecules typically cross cell membranes more easily

The OH production occurs in the presence of (i) ascorbate and Cu as catalysts or (ii) POx (Fig

Abstract Since their discovery in the 1970s, extracellular vesicles (EVs) have garnered significant scientific attention due to their involvement in diverse pathological processes, including tumorigenesis

Moreover, our recent studies have reported that glutamatergic neurons in the medial septum (MS) of the basal forebrain encode negative-valence sensory events and drive avoidance behavior (Zhang et al., 2018a,2018b), while its GABAergic neurons, specifically those expressing somatostatin, encode positive-valence events and drive appetitive behavior (Shen et al., 2022)