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Despite their similarity in signaling, there are major differences between the actions of insulin and IGF-1 in vivo

Also, in the late phase of M1 macrophage polarization, lactate-derived lactylation of histone lysine residues as observed in conditions of hypoxia and bacterial challenges served as an epigenetic modification that directly stimulated the expression of homeostatic genes that have been traditionally associated with M2-like macrophages (Zhang et al., 2019)

Eukaryotic Pathogens: A Systematic Review Microorganisms 11, 1567

Studies have also correlated the anti-biofilm activity of NAg to cellular ROS generation

Ultrapure water that prepared by Milli-Q water (Classic DI, ELGA, Marlow, UK) was used in the preparation of aqueous solutions