bacterial and host-derived glutathione are required to activate prfa Allosteric GSH binding primes for DNA binding. (A B) Glutathione Provides a Source of

Glutathione Provides a Source of Cysteine Essential for Intracellular Multiplication of Francisella tularensis PLOS Pathogens Listeria monocytogenes requires phosphotransferase systems to facilitate intracellular growth and virulence PMC RCSB PDB 5LRS: The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a 30 bp operator PrfA box motif C di AMP accumulation disrupts glutathione metabolism in Listeria monocytogenes Infection and Immunity Discovery of a glutathione utilization pathway in Francisella that shows functional divergence between environmental and pathogenic species ScienceDirect

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