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showed that simvastatin develops T helper 2 cell polarization through up-regulation of the chitinase family member Ym1 in dendritic cells (DCs) [45]

Ru(II)-Cyanine Complexes as Promising Photodynamic Photosensitizers for the Treatment of Hypoxic Tumours with Highly Penetrating 770nm Near-Infrared Light

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Trichloroethene exposure induces autoimmune reactions, leading to increased apoptosis, immune activation and the upregulation of PARP-1 expression following the development of anti-single-stranded DNA antibodies (78)

HOW INFLAMMATION LEADS TO DEPRESSION The evidence summarized in Table 2 highlights the established knowledge and recent evidence on how genetic predisposition and early life stress form a vulnerability for chronic immune dysregulation later in life, while acute infections, autoimmune disease and adverse lifestyle/metabolic factors act as triggers of sustained inflammation