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It is crucial to consult a healthcare provider before starting any new supplement, especially for individuals with pre-existing medical conditions or those taking other medications, to ensure safety and appropriateness

29 Underlying muscle diseases also predispose affected patients to statin-associated myopathies

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As discussed earlier, Koeth et al.'s study on gut microbiota-induced TMAO in stable patients undergoing cardiac evaluation showed significant dose-dependent associations between plasma L-carnitine levels and risks of coronary artery disease, peripheral artery disease, and overall CVD after correction for common CVD risk factors [18]

And sometimes there are interactions that reduce effectiveness or increase side effects