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Mutants (A30P and A53T) were more likely translocated to the IMS than the wild-type, and more -Syn would be translocated to IMS upon oxidative stress or cI inhibition (Vicario et al., 2019)

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[DOI] [PMC free article] [PubMed] [Google Scholar] He M

The combination approach of targeting two separate pathways produces results competitive with even the most effective single-agent therapies currently available