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Patients in this study had previously received one to three lines of therapy, including proteasome inhibitors

Does DES cause any permanent changes or just temporary muscle fullness

SIRT1 or SIRT3 was co-immunoprecipitated and eluted with elution buffer (Pierce # 21004), and their activities were measured using the SIRT GLOTM assay kits (Promega # G6450), according to the manufacturers instructions

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