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In addition, NNMT expression is not related to grade and stage in renal clear cell carcinoma but correlates negatively with tumor size, suggesting that it may play an important role in the initial malignant conversion phase (49)

Its found in high concentrations in animal products, especially red meat, and is essential for red blood cell formation, DNA synthesis, brain development, and nervous system function

Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover

Its also involved in synthesizing fatty acids and myelin via its role as a co-enzyme (2)