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Using the dye accessibility assay, we found that UT3-induced ubiquitin unfolding was largely diminished if either the ridge or the cleft was mutated or blocked (L55A, E145K, or UT3-C19 fusion

doi: 10.3389/fneur.2019.00013 86 ShuklaAWFoxSH

Ferroptosis suppressor protein 1 inhibition promotes tumor ferroptosis and anti-tumor immune responses in liver cancer

Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions

This article delves into the mechanisms of apoptosis in AD, revealing how A and tau protein deposits trigger apoptotic pathways, including the mitochondrial pathway and the death receptor pathway, leading to neuronal death