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The current limitation of our assay is applicability to transfectable cell lines, and higher expression of plasmid-encoded sensors relative to endogenous glucose-6-phosphate dehydrogenase

When there is an overaccumulation of glutamic acid, it becomes a potent neurotoxin

Alpha-lipoic acid ameliorates the epithelial mesenchymal transition induced by unilateral ureteral obstruction in mice

No FDA-approved pharmaceutical formulation exists, and the compound is not listed as a 503A bulk drug substance with positive compounding status

In addition, another study found that, despite having similar proteasome inhibitory effects, carfilzomib did not reduce neurite growth as BTZ did (Karademir et al., 2018