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14.4 MOUNJARO Use in Combination with Basal Insulin with or without Metformin in Adult Patients with Type 2 Diabetes Mellitus SURPASS-5 (NCT04039503) was a 40-week double-blind trial that randomized 475 adult patients with type 2 diabetes mellitus with inadequate glycemic control on insulin glargine 100 units/mL, with or without metformin, to subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or placebo

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Zhao Y.C., Zhang Y., Nasser A., Hong T., Wang Z., Sun A., Moldovan L., Edwards L.S., Passam F., Butcher K.S., et al

Plant Cell 16, 34603479

Green Synthesis of Fluorescent N-doped Carbon Quantum Dots from Castor Seeds and Their Applications in Cell Imaging and pH Sensing

K + efflux-dependent activation is reportedly unrelated to mitochondrial bioenergetics 41 , while Imiquimod and CL097 trigger K + efflux-independent NLRP3 activation by inhibiting mitochondrial complex I 41