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NNMT inhibition with 5-Amino-1MQ reduced white adipose tissue mass by ~35% in diet-induced obese mouse models without suppressing food intake, suggesting energy expenditure modulation

Elastography assessments The real-time B-mode ultrasound-based attenuation imaging (ATI) and the real-time 2-dimensional shear wave elastography (2D-SWE) were used to examine the liver steatosis and fibrosis pre- and post-study