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Loss of DPEP1 markedly relieved FA- or cisplatin-induced AKI by altering the apoptosis and ferroptosis, but not the pyroptosis or necroptosis

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doi: 10.1038/ncomms7734 99 IrapordaCErreaARomaninDECayetDPereyraEPignataroOet al

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Physiol.-Heart Circ

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Although traditional cytotoxic agents remain the primary focus, recent research has started to explore the potential of incorporating small-molecule inhibitors as functional payloads in ADC therapies, such as PARP inhibitors [111, 112], CDK inhibitors [113, 114], and immune-modulating agents [115,116,117]

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