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They include CAMP-response element binding protein (CREB), SP1 transcription factor (SP1), transcription factor AP-2 (AP2), proliferator-activated receptor alpha (PPAR), all activating GPX4 expression, while Krppel-like transcription factor 2 (KLF2) and CAMP-response element modulator (CREM), both repress its protein expression [7]

In addition, elevated cortisol will cause thyroid hormone receptor insensitivity meaning that even if T3 levels are high enough, they may not be able to bind normally to receptor sites

Mass spectrometry only measures for what we are looking for, whereas ELISA can also cover metabolites of the toxins we are looking for

8 Conclusion and future perspectives This review elucidates how obesity induces OS through metabolic, endocrine, inflammatory, and gut microbiota pathways

Spinach, kale, broccoli, sunflower seeds, and nuts like almonds and hazelnuts and even peanut butter are packed with vitamin E