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*Correspondence: Xin-Guang Qiu, [email protected] This article was submitted to Thyroid Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

range 0.9-3h depending on body weight) ~1.7-1.9 hours (subcutaneous) Initial: ~13 min (t), Terminal: ~1.7 hours (t) ~1-2 hours (exogenous plasma)

Discussion Using a vitamin B 12 deficiency phenotype definition, consistent with previous reports [1, 2], there were 487 (6.8%) deficient individuals of White European ancestry receiving metformin in the UKB cohort out of a total of 7173

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Zhang, G., Wang, Y., Zhang, Y., Wan, X., Li, J., Liu, K., Wang, F., Liu, Q., Yang, C., Yu, P., Huang, Y., Wang, S., Jiang, P., Qu, Z., Luan, J., Duan, H., Zhang, L., Hou, A., Jin, S., Wu, E