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In the body, they can act like signals: hormones, messengers, molecular switches

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Occasionally, similar cells may be seen in the underlying dermis (Figure 5.13), indicating invasion

However, there are additional warning signs that can alert you to possible nodular melanoma

These include: Albright syndrome, a genetic disorder that can affect the skin and bones Congenital melanocytic nevus, a type of birthmark that appears at birth or in the first year of life Congenital smooth muscle hamartoma, a birthmark often present from birth or noticed in the first year of life Overdevelopment of certain pieces of tissue such as adrenal gland, limb, fingers, or toes Post-inflammatory hyperpigmentation, where skin becomes darker after it has been damaged Smooth muscle hamartoma, a rare, benign, skin growth often present at birth or in early infancy Underdevelopment of underlying structures such as the breast, body fat, limb, etc