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First, GHKCu(II) has an anti-inflammatory effect by protecting the tissue from oxidative damage and by suppressing local inflammatory signals (i.e

Jiang C, Zhou L, Hu W, Luo J, Nezamzadeh-Ejhieh A, Ouyang J, Liu X, Pan Y, Cui S, Liu J

Instead, it downregulates the expression of MC1R, MITF, and TYR-related proteins to inhibit melanin formation [91]

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Viral infections, on the other hand, increase anaerobic glycolysis and hypoxia, resulting in high levels of ROS and lactate (34)