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Yes works through pituitary Yes works through pituitary No not a GH axis compound Table 1 Comparison of key parameters across three peptides

10.1016/j.freeradbiomed.2016.04.197 28

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As SMA can cause a person to have fewer motor neurons in their spinal cords, the spasticity that some people with SMA experience occurs when the muscles are not well-controlled by motor neurons