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13 M Dihexa and 2.5 ng/ml HGF or 10 13 M Nle1-AngIV and 2.5 ng/ml of HGF produced a near ceiling effect, similar to biological responsive doses of each ligand alone ( To further strengthen this perceived commonality of mechanism, the novel HGF antagonist Hinge was employed and evaluated for its effects on hippocampal neurons stimulated with AngIV analogues and HGF

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About 1020% of patients are non-responders or modest responders

While these treatment approaches, both behavioral and pharmacological, hold promise for alleviating METH-induced neurological damage, their long-term efficacy, potential side effects, and real-world feasibility remain significant concerns

Besides, CD38 can protect MM cells from apoptosis caused by a miRNA, miR-26a