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These variants not only determine disease susceptibility but also reshape tissue-specific epigenomic landscapes (Ling et al., 2022)

Chronic heavy drinking induces the microsomal ethanol-oxidizing system (MEOS) and CYP2E1 enzyme upregulation, increasing ethanol clearance speed while simultaneously generating reactive oxygen species that accelerate hepatocellular damage

In addition to de novo lipid synthesis, the loss of G6PD function also led to impaired NOS2 activity in Ms activated by LPS (61) or by IFN- and infected by Trypanosoma cruzi (62)

doi: 10.15324/kjcls.2021.53.3.201 79 FendlB.WeissR.EichhornT.LinsbergerI.AfonyushkinT.PuhmF.et al

Zhang et al., Multimodal photoacoustic imaging-guided regression of corneal neovascularization: a non-invasive and safe strategy