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For example, MetaPhlAn [89] and Kraken [90] enable taxonomic classification from shotgun metagenomic data, while QIIME2 [91] (Quantitative Insights into Microbial Ecology), RDP (Ribosomal Database Project) Classifier [98] and Phyloseq [92] provide pipelines for analyzing 16S rRNA sequencing data

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The expressions of GRK2 and adrenergic receptors are decreased in the aorta but not in mesenteric arteries of NG-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats, that is accompanied by decreased 1 -adrenergic receptor-induced vasoconstriction along with increased 2 -adrenergic receptor-mediated vasodilation

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