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Conversely, administration of the colony stimulating factor-1 receptor (CSF-1R) inhibitor, PLX3397, in a mouse model of stroke eliminated microglia, resulting in increased infarct size, neuronal signaling dysregulation, and cell death, which was reversed markedly by microglial repopulation (Szalay et al., 2016)

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Nutritional profile of bone broth Bone broth is simple to make, however, the nutritional value will vary depending on the bones used, how long they are cooked for and what additions are included

Human, randomized split-face