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The area under the curve clearly showed such changes (Figures 4B, D, F)

To determine whether this was the case, we constructed a triple mutant, trxA , trxC , gshA

Efficacy and safety of early-start deferiprone in infants and young children with transfusion-dependent beta thalassemia: evidence for iron shuttling to transferrin in a randomized, double-blind, placebo-controlled, clinical trial (START)

However, it faces persistent challenges, including limited efficiency, restricted payload capacity, and variability in patient response, highlighting the need for continued optimization [51]