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Tofersen is an ASO that reduces SOD1 protein synthesis by mediating the degradation of SOD1 mRNA

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Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia

In mature spermatocytes, mtDNA molecules may increase in response to higher ATP demand, providing energy reserves for sperm motility [66, 67]

Segments S5, S6 and extracellular pore loops (P-loops) connecting S5 and S6 in each domain create the pore domain through which Na + ions pass, containing the selectivity filter