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The authors suggest that either methyl-B12 and adenosyl-B12 should be given together, or either cyano-B12 or hydroxo-B12 on their own, both of which can be converted into both active forms

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Although surgery can improve function to some extent, it remains essentially a palliative measure that cannot reverse the degenerative process, and it may be accompanied by a series of intraoperative and postoperative risks, such as infection, bleeding, and implant failure

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OPRM1 (opioid receptor mu 1) increases 1,294%, KCND1 increases 845%, and SLC8A2 increases 737%