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8 , eade5019 (2023)

Sirolimus in renal transplantation

Carbon and energy metabolism is regulated by a complex net of nutrient sensors, growth hormone receptors, several downstream signaling pathways, and canonical transcription factors such as the nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-kB), the activator protein 1 (AP-1), the nuclear factor of activated T-cells (NFAT), and others (Postic et al., 2007

104 - 114 Creative Commons This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence ( which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited

311 The rapid degradation of mRNA can be addressed through chemical modification techniques and carrier encapsulation methods for protection