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There are three isoforms of CPTI, each present in characteristic tissues, CPTIA in liver and kidney, CPTIB in heart and skeletal muscle and CPTIC in the brain, and while CPTIA and CPTIB are the main enzymes for the transfer of long-chain fatty acids into mitochondria for oxidation, the lesser-known CPTIC may be a sensor of lipid metabolism in neurons

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212 Ketogenic diets are very low in carbohydrate, high in fat, and adequate in protein, and are used to treat epilepsy and obesity