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Gender disparity impacts on thymus aging and LHRH receptor antagonist-induced thymic reconstitution following chemotherapeutic damage

330 Another PRMT5 inhibitor, JNJ-64619178, has shown long-term PRMT5 inhibition and potent anti-tumor effect in lung, pancreatic, and hematological tumors

Subsequently, the heterodimer (HIF-:HIF-) migrates to hypoxic response elements (HREs) of the target gene and activates the transcription of multiple genes involved in multiple cellular pathways (35)

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doi: 10.1038/s41420-021-00553-6