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The honest clinical picture is a little different, and a lot calmer

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Needle less injections also come with a reduced risk of needle-related injuries

The presence of funnel plot asymmetry also suggests potential publication bias, which warrants further scrutiny

For superior sagittal sinus pressure recording, we made a single burr hole in the rostral part of the sagittal suture, above the superior sagittal sinus, and cannulated superior sagittal sinus anterior part by Braun intravenous cannulas, and then, we laparatomized rats for portal vein, inferior vena cava and abdominal aorta pressure recording