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Description

J., Budiman, H., Ruebsamen, H., Nagel, D

In our work on another PLP enzyme, alanine racemase, we determined the free energy profiles for protiated and deuterated alanine.[79] External aldimine formation in alanine racemase indeed shows a deuterium binding isotope effect of 1.26 0.07 and 1.27 0.07 for the LD and DL directions, respectively, which are relatively large