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Regulatory Effects of Neuroinflammatory Responses Through Brain-Derived Neurotrophic Factor Signaling in Microglial Cells

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None of the Marketing Authorisation Holders in the UK use any clinical evidence for optimal dosage of 3 monthly treatment and base the information written in their Patient Information Leaflet upon BNF Guidelines and the Martindale Drug Reference book

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Dosing, in Practice Commonly observed research protocols land around 50 mg/day to start, titrating to 100 mg/day, taken orally, usually morning and fasted