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The data is limited, and the use of L-arginine in patients with a history of heart attack or kidney disease is generally contraindicated, since L-arginine can actually increase the risk for complications in these populations. Under the guidance of your doctor, dietary strategies, along with medication, will likely also be implemented to help lower blood pressure

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Gut microbiome-derived metabolite trimethylamine n-oxide induces aortic stiffening and increases systolic blood pressure with aging in mice and humans