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Under inflammatory conditions, high levels of copper in serum can also induce oxidative stress and promote inflammatory response

This disorder of breathing during sleep has been associated with fatty acid accumulation in the liver and inflammation caused by frequent nocturnal hypoxia (NH), IR, OS, and adipokine dysregulation (99)

Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

Discussion The present pilot study demonstrated that antioxidant therapy with glutathione may reduce the pathological oxidative stress in the liver in NASH, preventing the progression from NAFLD to NASH

An Activation Likelihood Estimation meta-analysis revealed that patients with VCI consistently exhibit reduced ALFF and diminished FC at key nodes of the default mode network, specifically the precuneus and cingulate gyrus