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One proposed mechanism of the antibacterial effect of NS and TQ against a variety of Gram-positive and Gram-negative bacteria is by targeting them with ROS while at the same time protecting host tissues from OS through antioxidants (284) and selectively allowing probiotic LAB species to flourish (367)

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Consequently, due to these properties such as solubility and stability in various solvents, CU exhibits low bioavailability in the human body (Figure 1), necessitating a more complex mode of administration

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