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Whether it is exogenous VEGF or anti-VEGF is applied depends on the biological state of the injured tissue and its surrounding microenvironment

The review consolidates experimental evidence that supports the utilization of NAC in bone tissue engineering, underscoring its capacity to improve the osteogenic microenvironment and optimize bone regeneration outcomes

Care 15, 233239

Traumatic endplate fractures may cause a transient bone marrow oedema but chronic degenerative disc changes are required to trigger Modic changes