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After reconstitution, vials must be stored at 2, 8 degrees C and used within 30 days

A phase I, first-in-human study of TAK-164, an antibody-drug conjugate, in patients with advanced gastrointestinal cancers expressing guanylyl cyclase C

10.1016/j.redox.2019.101107 51 DollS.FreitasF

Cancer cells become easily addicted to glucose and glutamine, as their withdrawal can induce cell death

Through the study of the animal model of NIHL, Foxo3 knockout mice were more seriously damaged than those of normal mice after the same intensity of noise exposure, and the severity of hearing loss increased significantly, indicating that Foxo3 is an important protective gene for mice to maintain hearing after noise exposure