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Brimonidine is the only approved molecule in its class medication for long-term glaucoma treatment

10.1111/j.1745-7254.2005.00081.x Acta Pharmacol

Previous genome-wide identification of direct binding sites of BZR1 coupled with transcriptome profiling showed that BZR1 binds to promoters of both BR-repressed and -induced genes 5,15